The IT support for scientific experimenting and e-science is currently not at the level of maturity of the support enterprises obtain. Since recently there is a trend of reusing existing enterprise software and related concepts for scientific experiments, scientific workflows and simulation. Most notably these are the workflow technology, which is widely used in business process management (BPM), and integration paradigms like the service oriented architecture (SOA). In this work we give an overview of open issues in the support for scientific experiments and possible approaches to addressing them in a service-based environment. We identify the need for enhancing the BPM practices, technologies and techniques in order to render them applicable in the area of scientific experimenting. We stress on the even greater importance of workflow flexibility and also show why flexibility techniques are crucial when it is about improving the IT support for scientists.